Molecular Formula | C18H11F3N2O |
Molar Mass | 328.29 |
Density | 1.346±0.06 g/cm3(Predicted) |
Boling Point | 466.3±45.0 °C(Predicted) |
Solubility | DMSO: ≥ 30 mg/mL |
pKa | 2.46±0.10(Predicted) |
Storage Condition | -20℃ |
In vitro study | In gynecological cancer cells, PFK158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis. PFK158 treatment can sensitize chemotherapy-resistant cells and induce cell death. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.046 ml | 15.231 ml | 30.461 ml |
5 mM | 0.609 ml | 3.046 ml | 6.092 ml |
10 mM | 0.305 ml | 1.523 ml | 3.046 ml |
5 mM | 0.061 ml | 0.305 ml | 0.609 ml |